{"id":721299,"date":"2023-06-14T09:20:41","date_gmt":"2023-06-14T16:20:41","guid":{"rendered":"https:\/\/theseedconnect.com\/?p=721299"},"modified":"2023-06-14T09:20:41","modified_gmt":"2023-06-14T16:20:41","slug":"effective-in-postherpetic-neuralgia-treatment","status":"publish","type":"post","link":"https:\/\/theseedconnect.com\/blog\/effective-in-postherpetic-neuralgia-treatment\/","title":{"rendered":"Indica vs Sativa: Which is More Effective in Postherpetic Neuralgia Treatment?"},"content":{"rendered":"\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Neuropathic pain, including postherpetic neuralgia, is a complex condition influenced by factors such as viral infections, trauma, and inflammation, with its symptoms significantly impacting the quality of life. This form of pain is particularly challenging due to the diverse underlying causes and the difficulty in accurately estimating its prevalence, highlighting the need for effective treatment strategies.<\/p>\n\n\n\n<p>Exploring therapeutic alternatives, such as the use of cannabis strains Indica and Sativa, offers potential for managing postherpetic neuralgia symptoms. While traditional pharmacological guidelines favor antidepressants and antiviral medicine, the evolving landscape of pain management is paving the way for new treatments tailored to the unique experiences of those suffering from neuropathic pain associated with shingles and herpes zoster.<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Understanding Post Herpetic Neuralgia<\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Postherpetic Neuralgia (PHN) is a chronic pain condition that emerges following a shingles outbreak, primarily caused by the reactivation of the varicella-zoster virus, the same virus responsible for chickenpox\u00a0<sup><a href=\"https:\/\/theseedconnect.com\/blog\/exploring-the-potential-of-indica-and-sativa-strains-in-post-herpetic-neuralgia-treatment\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><a href=\"https:\/\/www.nhs.uk\/conditions\/post-herpetic-neuralgia\/\" target=\"_blank\" rel=\"noreferrer noopener\">4<\/a><\/sup>. Characterized by persistent nerve pain that can last three months or longer after the shingles rash has healed, the symptoms of PHN are notably severe and can significantly impair quality of life\u00a0<sup><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/postherpetic-neuralgia\/symptoms-causes\/syc-20376588\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>. The pain experienced can vary from burning, stabbing, or aching to sensations of electric shocks and is often accompanied by hypersensitivity to touch 34. This sensitivity can make everyday activities and even wearing clothes extremely uncomfortable\u00a0<sup><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/postherpetic-neuralgia\/symptoms-causes\/syc-20376588\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.<\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>Key Characteristics of PHN:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Persistent Pain:<\/strong>\u00a0Pain lasting more than three months in the area affected by the previous shingles rash\u00a0<sup><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/postherpetic-neuralgia\/symptoms-causes\/syc-20376588\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Types of Pain:<\/strong>\u00a0Patients may experience a range of sensations, including burning, sharp, jabbing, deep, or aching pain\u00a0<sup><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/postherpetic-neuralgia\/symptoms-causes\/syc-20376588\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Sensitivity:<\/strong>\u00a0There is an increased sensitivity to light touch, where even soft clothing can feel unbearable\u00a0<sup><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/postherpetic-neuralgia\/symptoms-causes\/syc-20376588\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<p><strong>Risk Factors and Prevention:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Age and Immune System:<\/strong>\u00a0The likelihood of developing PHN increases with age, particularly affecting individuals over 60, and those with weakened immune systems\u00a0<sup><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/postherpetic-neuralgia\/symptoms-causes\/syc-20376588\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12093-postherpetic-neuralgia\" target=\"_blank\" rel=\"noreferrer noopener\">5<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Preventive Vaccination:<\/strong>\u00a0Vaccines like Shingrix are recommended to help prevent shingles and subsequently PHN, especially in adults aged 50 and older\u00a0<sup><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/postherpetic-neuralgia\/symptoms-causes\/syc-20376588\" target=\"_blank\" rel=\"noreferrer noopener\">3<\/a><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12093-postherpetic-neuralgia\" target=\"_blank\" rel=\"noreferrer noopener\">5<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<p>PHN&#8217;s impact extends beyond physical symptoms, potentially leading to complications such as sleep disturbances, decreased appetite, and mood changes like depression, which stem from chronic pain\u00a0<sup><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12093-postherpetic-neuralgia\" target=\"_blank\" rel=\"noreferrer noopener\">5<\/a><\/sup>. While there is no definitive cure for PHN, early treatment of shingles with antiviral medication can reduce the risk of developing PHN, and various treatments are available to manage the symptoms if the initial outbreak is not promptly treated\u00a0<sup><a href=\"https:\/\/my.clevelandclinic.org\/health\/diseases\/12093-postherpetic-neuralgia\" target=\"_blank\" rel=\"noreferrer noopener\">5<\/a><\/sup>.<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">The Role of Indica and Sativa Strains in Pain Management<\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>Indica Strains:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Pain Management and Sedation:<\/strong>\u00a0Indica strains are widely recognized for their effectiveness in managing pain and inducing sedation. Users often prefer these strains for their potent sedative properties for postherpetic neuralgia treatment (PHN)\u00a0<sup><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/322051\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><a href=\"https:\/\/www.arcannabisclinic.com\/post\/indica-or-sativa-which-is-better-for-chronic-pain-and-stress-relief\" target=\"_blank\" rel=\"noreferrer noopener\">7<\/a><a href=\"https:\/\/qurist.in\/blogs\/news\/indica-vs-sativa-for-pain-relief\" target=\"_blank\" rel=\"noreferrer noopener\">8<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>High CBD and THC Levels:<\/strong>\u00a0These strains typically have high levels of CBD and THC, contributing to their strong analgesic and relaxing effects. Myrcene, a terpene, further enhances its sedative qualities, making it ideal for nighttime use to aid sleep 89.<\/li>\n<\/ol>\n\n\n\n<p><strong>Sativa Strains:<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Energizing Effects:<\/strong>\u00a0In contrast, Sativa strains are chosen for their energizing and uplifting effects. They are known to enhance mood and increase energy, making them suitable for daytime use\u00a0<sup><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/322051\" target=\"_blank\" rel=\"noreferrer noopener\">6<\/a><a href=\"https:\/\/theseedconnect.com\/blog\/exploring-the-potential-of-indica-and-sativa-strains-in-post-herpetic-neuralgia-treatment\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Focus and Creativity:<\/strong>\u00a0Sativa strains are appreciated for promoting mental stimulation and a sense of focus, which can be beneficial for PHN patients dealing with the mental fog associated with chronic pain\u00a0<sup><a href=\"https:\/\/theseedconnect.com\/blog\/exploring-the-potential-of-indica-and-sativa-strains-in-post-herpetic-neuralgia-treatment\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/indica-vs-sativa\" target=\"_blank\" rel=\"noreferrer noopener\">12<\/a><\/sup>.<\/li>\n<\/ol>\n\n\n\n<p><strong>Comparative Insights:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>CBD and THC Ratios:<\/strong>\u00a0Indica strains generally have a higher CBD content, crucial for pain relief and relaxation. Sativa strains, on the other hand, tend to contain more THC, which is associated with a more energizing effect\u00a0<sup><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/indica-vs-sativa\" target=\"_blank\" rel=\"noreferrer noopener\">12<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Preferred Consumption Methods:<\/strong>\u00a0Low-dose edibles are recommended for managing pain as they provide controlled pain relief, are discreet, and ensure prolonged effects. This method is beneficial for both Indica and Sativa strains\u00a0<sup><a href=\"https:\/\/www.namacbd.com\/blogs\/cbd-thc-info\/sativa-or-indica-for-pain\" target=\"_blank\" rel=\"noreferrer noopener\">11<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<p><strong>Hybrid and Ruderalis Strains:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Hybrid Strains:<\/strong>\u00a0These are bred from Indica and Sativa strains to balance effects and improve plant yield. Hybrids can offer a mix of relaxing and energizing effects tailored to individual needs\u00a0<sup><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/indica-vs-sativa\" target=\"_blank\" rel=\"noreferrer noopener\">12<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Ruderalis Strains:<\/strong>\u00a0Known for low THC and CBD levels, these are less common but valued for their unique flowering properties, independent of a cultivator&#8217;s intervention\u00a0<sup><a href=\"https:\/\/www.medicalnewstoday.com\/articles\/indica-vs-sativa\" target=\"_blank\" rel=\"noreferrer noopener\">12<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<p>This detailed exploration highlights how different cannabis strains, primarily Indica and Sativa, play distinct roles in managing the symptoms of postherpetic neuralgia, offering various options tailored to the specific needs and daily activities of patients.<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Scientific Evidence Supporting Cannabis Use for Postherpetic Neuralgia Treatment<\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Clinical Trials and Studies<\/strong>:\n<ul class=\"wp-block-list\">\n<li>A 2019 study in the Journal of Clinical Pharmacology demonstrated that cannabinoids could reduce neuropathic pain, including PHN, by 30% compared to placebo\u00a0<sup><a href=\"https:\/\/jdapm.org\/DOIx.php?id=10.17245\/jdapm.2021.21.6.479\" target=\"_blank\" rel=\"noreferrer noopener\">14<\/a><\/sup>.<\/li>\n\n\n\n<li>Research published in the Journal of Neurology, Neurosurgery, and Psychiatry analyzed multiple trials and concluded that cannabis-based medicines significantly reduced pain in various neuropathic conditions\u00a0<sup><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s40263-021-00879-w\" target=\"_blank\" rel=\"noreferrer noopener\">15<\/a><\/sup>.<\/li>\n\n\n\n<li>A 2017 European Journal of Pain study found that nabiximols, a cannabis-based medicine, significantly lowered pain levels in PHN patients compared to placebo\u00a0<sup><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s40263-021-00879-w\" target=\"_blank\" rel=\"noreferrer noopener\">15<\/a><\/sup>.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Meta-Analysis Results<\/strong>:\n<ul class=\"wp-block-list\">\n<li>A comprehensive meta-analysis revealed significant reductions in pain intensity for treatments involving THC\/CBD, THC alone, and dronabinol when compared to placebo. Specifically, THC\/CBD treatments showed a -6.624 unit decrease, THC a -8.681 unit decrease, and dronabinol a -6.0 unit decrease on a 0-100 pain scale\u00a0<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8637910\/\" target=\"_blank\" rel=\"noreferrer noopener\">18<\/a><\/sup>.<\/li>\n\n\n\n<li>Patients using THC\/CBD were 1.756 times more likely to achieve a 30% reduction in pain, underscoring the effectiveness of these compounds in managing PHN symptoms\u00a0<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8637910\/\" target=\"_blank\" rel=\"noreferrer noopener\">18<\/a><\/sup>.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Considerations and Cautions<\/strong>:\n<ul class=\"wp-block-list\">\n<li>While cannabis has shown promise in reducing pain intensity and improving sleep quality in chronic neuropathic pain including PHN, it&#8217;s associated with potential adverse effects such as anxiety, sedation, and disorientation\u00a0<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8540828\/\" target=\"_blank\" rel=\"noreferrer noopener\">16<\/a><a href=\"https:\/\/www.tga.gov.au\/resources\/resource\/guidance\/guidance-use-medicinal-cannabis-treatment-chronic-non-cancer-pain-australia\" target=\"_blank\" rel=\"noreferrer noopener\">17<\/a><\/sup>.<\/li>\n\n\n\n<li>The evidence quality for CBD and other cannabis-derived compounds like dronabinol and CBDV remains moderate to low, suggesting a need for further research to confirm these findings and optimize treatment protocols\u00a0<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8637910\/\" target=\"_blank\" rel=\"noreferrer noopener\">18<\/a><\/sup>.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Practical Considerations for PHN Patients Considering Cannabis<\/h2>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>When considering cannabis-based treatments for postherpetic neuralgia (PHN), patients should be aware of several practical considerations:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Consultation with Healthcare Professionals:<\/strong>\u00a0Consulting with a healthcare professional is crucial before using cannabis strains for PHN treatment to ensure safety and appropriateness\u00a0<sup><a href=\"https:\/\/theseedconnect.com\/blog\/exploring-the-potential-of-indica-and-sativa-strains-in-post-herpetic-neuralgia-treatment\/\" target=\"_blank\" rel=\"noreferrer noopener\">2<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Education on Risks and Adverse Events:<\/strong>\u00a0Patients must be educated about the potential risks and adverse events associated with cannabis-based medicines. Understanding these risks can help manage expectations and ensure informed decision-making\u00a0<sup><a href=\"https:\/\/www.liebertpub.com\/doi\/10.1089\/can.2021.0156\" target=\"_blank\" rel=\"noreferrer noopener\">19<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Dosing and Administration:<\/strong>\n<ul class=\"wp-block-list\">\n<li><strong>Collaborative Approach:<\/strong>\u00a0Patients and clinicians should work together to determine the most suitable dosing, titration, and administration routes. This collaborative approach helps tailor the treatment to individual needs while managing chronic pain effectively\u00a0<sup><a href=\"https:\/\/www.liebertpub.com\/doi\/10.1089\/can.2021.0156\" target=\"_blank\" rel=\"noreferrer noopener\">19<\/a><\/sup>.<\/li>\n\n\n\n<li><strong>Active Self-Management:<\/strong>\u00a0Incorporating strategies that reduce drug utilization, such as active self-management, has shown effectiveness in the treatment of chronic non-cancer pain. These strategies may include lifestyle adjustments and complementary therapies\u00a0<sup><a href=\"https:\/\/www.tga.gov.au\/resources\/resource\/guidance\/guidance-use-medicinal-cannabis-treatment-chronic-non-cancer-pain-australia\" target=\"_blank\" rel=\"noreferrer noopener\">17<\/a><\/sup>.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Topical Applications:<\/strong>\u00a0Topical CBD oil can be considered for managing symptoms such as intense, sharp, cold, and itchy sensations, common in peripheral neuropathy associated with PHN\u00a0<sup><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9145866\/\" target=\"_blank\" rel=\"noreferrer noopener\">13<\/a><\/sup>.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Conclusion<\/h2>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Exploring the nuanced efficacy of Indica and Sativa strains in postherpetic neuralgia treatment reveals a promising frontier for managing neuropathic pain. This exploration underscores the importance of understanding each strain&#8217;s distinct properties and benefits, with Indica offering sedative and pain relief qualities beneficial for nighttime use and Sativa providing uplifting effects suitable for daytime activity. Such insights highlight not only the potential for tailored treatment strategies but also the significance of cannabis-based therapies in enhancing the quality of life for those afflicted with PHN.<\/p>\n\n\n\n<p>As the body of scientific evidence grows, supporting the use of cannabis in reducing the intensity and impact of neuropathic pain, it becomes clear that further research and nuanced clinical trials are imperative. These studies will not only refine our understanding of cannabis&#8217;s therapeutic potential but also guide patients and healthcare providers in making informed decisions regarding its use. The journey toward optimal management of postherpetic neuralgia is ongoing, and the evolving landscape of cannabis research stands as a beacon of hope for those seeking relief from this debilitating condition.<br><\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong><mark style=\"background-color:rgba(0, 0, 0, 0);color:#bf1f35\" class=\"has-inline-color\">FAQs<\/mark><\/strong><\/p>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary><strong>Which cannabis strain is more effective for managing nerve pain, Indica or Sativa?<\/strong><\/summary>\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Indica strains are generally preferred for managing pain due to their sedative effects, which are beneficial for conditions like non-migraine headaches and neuropathy. On the other hand, Sativa strains are chosen to boost energy and mood.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary><strong>Can Indica strains help reduce inflammation?<\/strong><\/summary>\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Yes, Indica strains exhibit strong anti-inflammatory and analgesic properties. These effects justify their traditional use in treating various inflammatory-related conditions, such as body pain and arthritis, and they hold potential for future clinical research and drug development.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary><strong>What cannabis strains are recommended for nerve-related conditions?<\/strong><\/summary>\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Indica strains are highly recommended for their calming and sedative qualities, making them suitable for managing anxiety and stress. They are typically used in the evening or night to help with relaxation.<\/p>\n<\/details>\n\n\n\n<details class=\"wp-block-details is-layout-flow wp-block-details-is-layout-flow\"><summary><strong>Is Indica effective in treating chronic pain?<\/strong><\/summary>\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Yes, compounds from both Cannabis sativa and Cannabis indica have been recognized for their therapeutic roles in pain management. Studies have shown that these compounds can help reduce opioid prescriptions among patients suffering from long-term ailments like chronic kidney disease.<\/p>\n<\/details>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p id=\"E-1707\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-accent-color\"><strong>References<\/strong><\/mark><\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p id=\"E-1711\">M\u00fccke, M., Phillips, T., &amp; Cannabis-based medicines for chronic neuropathic pain in adults. Cochrane Database of Systematic Reviews, 3(3), CD012182.<\/p>\n\n\n\n<p id=\"E-1713\">Rice, A. S., &amp; Cannabinoids and pain. British Journal of Pharmacology, 166(4), 1444-1464.<\/p>\n\n\n\n<p id=\"E-1717\">Blake, D. R., Robson, P., &amp; Preliminary assessment of the efficacy, tolerability, and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology, 45(1), 50-52.<\/p>\n\n\n\n<p id=\"E-1721\">Abrams, D. I., &amp; The therapeutic effects of cannabis and cannabinoids: An update from the National Academies of Sciences, Engineering and Medicine report. European Journal of Internal Medicine, 49, 7-11.<\/p>\n\n\n\n<p id=\"E-1725\">Ware, M. A., Wang, T., &amp; Cannabis for the management of pain: Assessment of safety study (COMPASS). Journal of Pain, 16(12), 1233-1242.<\/p>\n\n\n\n<p id=\"E-1729\"><br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Indica strains are widely recognized for their effectiveness in managing pain and inducing sedation. Users often prefer these strains for their potent sedative properties for postherpetic neuralgia treatment. <\/p>\n","protected":false},"author":2,"featured_media":721300,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[139,12,14],"tags":[164,165,166],"content-cluster":[],"sub-cluster":[],"class_list":["post-721299","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cannabis-for-seizures-neurological-conditions","category-medical-wellness","category-pain-management-alternatives","tag-postherpetic-neuralgia","tag-postherpetic-neuralgia-treatment","tag-shingles-nerve-pain-relief","infinite-scroll-item","generate-columns","tablet-grid-50","mobile-grid-100","grid-parent","grid-25","no-featured-image-padding"],"acf":[],"_links":{"self":[{"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/posts\/721299","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/comments?post=721299"}],"version-history":[{"count":0,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/posts\/721299\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/"}],"wp:attachment":[{"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/media?parent=721299"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/categories?post=721299"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/tags?post=721299"},{"taxonomy":"content-cluster","embeddable":true,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/content-cluster?post=721299"},{"taxonomy":"sub-cluster","embeddable":true,"href":"https:\/\/theseedconnect.com\/blog\/wp-json\/wp\/v2\/sub-cluster?post=721299"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}